Wei Li
Shantou University Medical College, China
Biography
Wei Li has his expertise and passion in fundamental biological and medical research, particular in areas related to three-dimensional structures of biologically relevant macromolecules and experimental data-driven molecular dynamics (MD) simulation and molecular docking and modeling. After years of wet- and dry-lab experience in research (including solution-state NMR, python programming and high-performance computer usage), he has developed a set of skills to uncover novel structural/functional insights through computational analysis of experimentally determined structures of biological molecules. Here, as an example in spinal muscular atrophy-related studies, his work presented the first attempt to link clinically identified SMA-linked mutations of SMN1 to the structural/functional deficiency of SMN, the protein that is critical to this neuromuscular disease.